Welcome to the Genazzani lab. It was established in 2004 and is part of the Department of Pharmaceutical Sciences
of the Università del Piemonte Orientale. The main lab is located in the "Alcoa" Building
an architectural masterpiece by Renzo Piano,
while the pharmacogenetics section is now located in a purpose-built laboratory in the "Wild" Building
(www.pharm.unipmn.it/), an example of urban re-conversion of industrial settings,
as it used to be a cotton industry.
Historically, Armando Genazzani has focused its interests in basic mechanisms underlying calcium signalling,
but in recent years a number of other research topics (for example, in the field of neuroscience and cancer biology)
have also been pursued by the lab. In recent years, many lab members are devoting their efforts to the possibility that NAMPT,
an enzyme involved in NAD synthesis, can be a pharmacological target in cancer. The lab is now starting to maintain a webpage
on preclinical evidences that support the use of NAMPT inhibitors in cancer.
The lab also has strong ties with medicinal chemistry groups to pursue early drug discovery
(www.symech.it) and with clinicians to understand individual differences in drug responses
The lab always welcomes applications from talented undergraduates, graduates and post-doctoral fellows willing
to join our efforts and ideas for collaborations, including multidisciplinary approaches.