Publications

  1. Colombo, G, Travelli, C, Porta, C, Genazzani, AA. Extracellular nicotinamide phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4. iScience. 2022;25 (4):104147. doi: 10.1016/j.isci.2022.104147. PubMed PMID:35402885 PubMed Central PMC8990213.
  2. Villa, F, Di Filippo, A, Pierantozzi, A, Genazzani, A, Addis, A, Trifirò, G et al.. Orphan Drug Prices and Epidemiology of Rare Diseases: A Cross-Sectional Study in Italy in the Years 2014-2019. Front Med (Lausanne). 2022;9 :820757. doi: 10.3389/fmed.2022.820757. PubMed PMID:35252257 PubMed Central PMC8891228.
  3. Dematteis, G, Restelli, E, Vanella, VV, Manfredi, M, Marengo, E, Corazzari, M et al.. Calcineurin Controls Cellular Prion Protein Expression in Mouse Astrocytes. Cells. 2022;11 (4):. doi: 10.3390/cells11040609. PubMed PMID:35203261 PubMed Central PMC8870693.
  4. Antona, A, Varalda, M, Roy, K, Favero, F, Mazzucco, E, Zuccalà, M et al.. Dissecting the Mechanism of Action of Spiperone-A Candidate for Drug Repurposing for Colorectal Cancer. Cancers (Basel). 2022;14 (3):. doi: 10.3390/cancers14030776. PubMed PMID:35159043 PubMed Central PMC8834219.
  5. Colombo, G, Gelardi, ELM, Balestrero, FC, Moro, M, Travelli, C, Genazzani, AA et al.. Insight Into Nicotinamide Adenine Dinucleotide Homeostasis as a Targetable Metabolic Pathway in Colorectal Cancer. Front Pharmacol. 2021;12 :758320. doi: 10.3389/fphar.2021.758320. PubMed PMID:34880756 PubMed Central PMC8645963.
  6. Jommi, C, Listorti, E, Villa, F, Ghislandi, S, Genazzani, A, Cangini, A et al.. Variables affecting pricing of orphan drugs: the Italian case. Orphanet J Rare Dis. 2021;16 (1):439. doi: 10.1186/s13023-021-02022-w. PubMed PMID:34666819 PubMed Central PMC8527608.
  7. Tapella, L, Dematteis, G, Ruffinatti, FA, Ponzoni, L, Fiordaliso, F, Corbelli, A et al.. Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures. Cell Calcium. 2021;100 :102480. doi: 10.1016/j.ceca.2021.102480. PubMed PMID:34607180 .
  8. Lim, D, Dematteis, G, Tapella, L, Genazzani, AA, Calì, T, Brini, M et al.. Ca2+ handling at the mitochondria-ER contact sites in neurodegeneration. Cell Calcium. 2021;98 :102453. doi: 10.1016/j.ceca.2021.102453. PubMed PMID:34399235 .
  9. Ticci, C, Cassandrini, D, Rubegni, A, Riva, B, Vattemi, G, Matà, S et al.. Expanding the clinical and genetic spectrum of pathogenic variants in STIM1. Muscle Nerve. 2021;64 (5):567-575. doi: 10.1002/mus.27391. PubMed PMID:34368974 .
  10. Lim, D, Semyanov, A, Genazzani, A, Verkhratsky, A. Calcium signaling in neuroglia. Int Rev Cell Mol Biol. 2021;362 :1-53. doi: 10.1016/bs.ircmb.2021.01.003. PubMed PMID:34253292 .
  11. Aprile, S, Riva, B, Bhela, IP, Cordero-Sanchez, C, Avino, G, Genazzani, AA et al.. 1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry. ACS Med Chem Lett. 2021;12 (4):640-646. doi: 10.1021/acsmedchemlett.1c00034. PubMed PMID:33854704 PubMed Central PMC8040252.
  12. Serafini, M, Cargnin, S, Massarotti, A, Tron, GC, Pirali, T, Genazzani, AA et al.. What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications. J Med Chem. 2021;64 (8):4410-4429. doi: 10.1021/acs.jmedchem.1c00181. PubMed PMID:33847110 PubMed Central PMC8154580.
  13. Nikolaeva-Koleva, M, Butron, L, González-Rodríguez, S, Devesa, I, Valente, P, Serafini, M et al.. A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability. Sci Rep. 2021;11 (1):246. doi: 10.1038/s41598-020-80725-z. PubMed PMID:33420359 PubMed Central PMC7794549.
  14. Serafini, M, Cordero-Sanchez, C, Di Paola, R, Bhela, IP, Aprile, S, Purghè, B et al.. Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors. J Med Chem. 2020;63 (23):14761-14779. doi: 10.1021/acs.jmedchem.0c01305. PubMed PMID:33253576 PubMed Central PMC7735735.
  15. Cargnin, S, Shin, JI, Genazzani, AA, Nottegar, A, Terrazzino, S. Comparative efficacy and safety of trastuzumab biosimilars to the reference drug: a systematic review and meta-analysis of randomized clinical trials. Cancer Chemother Pharmacol. 2020;86 (5):577-588. doi: 10.1007/s00280-020-04156-3. PubMed PMID:33005979 .
  16. Dionisi, M, Ruffinatti, FA, Riva, B, Lim, D, Canta, A, Meregalli, C et al.. Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification. Int J Mol Sci. 2020;21 (19):. doi: 10.3390/ijms21197164. PubMed PMID:32998392 PubMed Central PMC7584002.
  17. Dematteis, G, Vydmantaitė, G, Ruffinatti, FA, Chahin, M, Farruggio, S, Barberis, E et al.. Proteomic analysis links alterations of bioenergetics, mitochondria-ER interactions and proteostasis in hippocampal astrocytes from 3xTg-AD mice. Cell Death Dis. 2020;11 (8):645. doi: 10.1038/s41419-020-02911-1. PubMed PMID:32811809 PubMed Central PMC7434916.
  18. Ruffinatti, FA, Lomazzi, S, Nardo, L, Santoro, R, Martemiyanov, A, Dionisi, M et al.. Assessment of a Silicon-Photomultiplier-Based Platform for the Measurement of Intracellular Calcium Dynamics with Targeted Aequorin. ACS Sens. 2020;5 (8):2388-2397. doi: 10.1021/acssensors.0c00277. PubMed PMID:32701269 PubMed Central PMC8009593.
  19. Addis, A, Genazzani, A, Trotta, MP, Magrini, N, Italian Medicines Agency's Scientific Committee and COVID-19 Crisis Unit. Promoting Better Clinical Trials and Drug Information as Public Health Interventions for the COVID-19 Emergency in Italy. Ann Intern Med. 2020;173 (8):654-655. doi: 10.7326/M20-3775. PubMed PMID:32543882 PubMed Central PMC7322772.
  20. Galli, U, Colombo, G, Travelli, C, Tron, GC, Genazzani, AA, Grolla, AA et al.. Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy. Front Pharmacol. 2020;11 :656. doi: 10.3389/fphar.2020.00656. PubMed PMID:32477131 PubMed Central PMC7235340.
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