Publications

  1. Foroutan, A, Corazzari, M, Grolla, AA, Colombo, G, Travelli, C, Genazzani, AA et al.. Identification of novel aza-analogs of TN-16 as disrupters of microtubule dynamics through a multicomponent reaction. Eur J Med Chem. 2022;245 (Pt 1):114895. doi: 10.1016/j.ejmech.2022.114895. PubMed PMID:36370553 .
  2. Tapella, L, Dematteis, G, Moro, M, Pistolato, B, Tonelli, E, Vanella, VV et al.. Protein synthesis inhibition and loss of homeostatic functions in astrocytes from an Alzheimer's disease mouse model: a role for ER-mitochondria interaction. Cell Death Dis. 2022;13 (10):878. doi: 10.1038/s41419-022-05324-4. PubMed PMID:36257957 PubMed Central PMC9579125.
  3. Lim, D, Tapella, L, Dematteis, G, Talmon, M, Genazzani, AA. Calcineurin Signalling in Astrocytes: From Pathology to Physiology and Control of Neuronal Functions. Neurochem Res. 2022; :. doi: 10.1007/s11064-022-03744-4. PubMed PMID:36083398 .
  4. Trapani, D, Tay-Teo, K, Tesch, ME, Roitberg, F, Sengar, M, Altuna, SC et al.. Implications of Oncology Trial Design and Uncertainties in Efficacy-Safety Data on Health Technology Assessments. Curr Oncol. 2022;29 (8):5774-5791. doi: 10.3390/curroncol29080455. PubMed PMID:36005193 PubMed Central PMC9406873.
  5. Costa, E, Grimaldi, G, Del Grosso, V, Isgrò, A, Genazzani, A. [Access to medicines for rare diseases: regulatory aspects and public health priorities.]. Recenti Prog Med. 2022;113 (7):415-424. doi: 10.1701/3850.38335. PubMed PMID:35852076 .
  6. Imperio, D, Grolla, AA, Moro, M, Bortolotto, V, Del Grosso, E, Genazzani, AA et al.. Functionalization of β-cyclodextrin with a urea-based PSMA ligand and preliminary studies on targeting prostate cancer cells. Bioorg Med Chem Lett. 2022;73 :128890. doi: 10.1016/j.bmcl.2022.128890. PubMed PMID:35839965 .
  7. Galai, E, Scotti, L, Gilardetti, M, Ucciero, A, Ferrante, D, Poluzzi, E et al.. Time-Trends of Drug-Drug Interactions among Elderly Outpatients in the Piedmont Region (Italy): A Population-Based Study. Int J Environ Res Public Health. 2022;19 (12):. doi: 10.3390/ijerph19127353. PubMed PMID:35742605 PubMed Central PMC9224286.
  8. Cordero-Sanchez, C, Pessolano, E, Riva, B, Vismara, M, Trivigno, SMG, Clemente, N et al.. CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy. Blood Adv. 2022;6 (15):4471-4484. doi: 10.1182/bloodadvances.2021006378. PubMed PMID:35696753 PubMed Central PMC9636319.
  9. Riva, B, Pessolano, E, Quaglia, E, Cordero-Sanchez, C, Bhela, IP, Topf, A et al.. STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39. Cell Calcium. 2022;105 :102605. doi: 10.1016/j.ceca.2022.102605. PubMed PMID:35636153 .
  10. Colombo, G, Travelli, C, Porta, C, Genazzani, AA. Extracellular nicotinamide phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4. iScience. 2022;25 (4):104147. doi: 10.1016/j.isci.2022.104147. PubMed PMID:35402885 PubMed Central PMC8990213.
  11. Villa, F, Di Filippo, A, Pierantozzi, A, Genazzani, A, Addis, A, Trifirò, G et al.. Orphan Drug Prices and Epidemiology of Rare Diseases: A Cross-Sectional Study in Italy in the Years 2014-2019. Front Med (Lausanne). 2022;9 :820757. doi: 10.3389/fmed.2022.820757. PubMed PMID:35252257 PubMed Central PMC8891228.
  12. Dematteis, G, Restelli, E, Vanella, VV, Manfredi, M, Marengo, E, Corazzari, M et al.. Calcineurin Controls Cellular Prion Protein Expression in Mouse Astrocytes. Cells. 2022;11 (4):. doi: 10.3390/cells11040609. PubMed PMID:35203261 PubMed Central PMC8870693.
  13. Antona, A, Varalda, M, Roy, K, Favero, F, Mazzucco, E, Zuccalà, M et al.. Dissecting the Mechanism of Action of Spiperone-A Candidate for Drug Repurposing for Colorectal Cancer. Cancers (Basel). 2022;14 (3):. doi: 10.3390/cancers14030776. PubMed PMID:35159043 PubMed Central PMC8834219.
  14. Colombo, G, Gelardi, ELM, Balestrero, FC, Moro, M, Travelli, C, Genazzani, AA et al.. Insight Into Nicotinamide Adenine Dinucleotide Homeostasis as a Targetable Metabolic Pathway in Colorectal Cancer. Front Pharmacol. 2021;12 :758320. doi: 10.3389/fphar.2021.758320. PubMed PMID:34880756 PubMed Central PMC8645963.
  15. Jommi, C, Listorti, E, Villa, F, Ghislandi, S, Genazzani, A, Cangini, A et al.. Variables affecting pricing of orphan drugs: the Italian case. Orphanet J Rare Dis. 2021;16 (1):439. doi: 10.1186/s13023-021-02022-w. PubMed PMID:34666819 PubMed Central PMC8527608.
  16. Tapella, L, Dematteis, G, Ruffinatti, FA, Ponzoni, L, Fiordaliso, F, Corbelli, A et al.. Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures. Cell Calcium. 2021;100 :102480. doi: 10.1016/j.ceca.2021.102480. PubMed PMID:34607180 .
  17. Lim, D, Dematteis, G, Tapella, L, Genazzani, AA, Calì, T, Brini, M et al.. Ca2+ handling at the mitochondria-ER contact sites in neurodegeneration. Cell Calcium. 2021;98 :102453. doi: 10.1016/j.ceca.2021.102453. PubMed PMID:34399235 .
  18. Ticci, C, Cassandrini, D, Rubegni, A, Riva, B, Vattemi, G, Matà, S et al.. Expanding the clinical and genetic spectrum of pathogenic variants in STIM1. Muscle Nerve. 2021;64 (5):567-575. doi: 10.1002/mus.27391. PubMed PMID:34368974 .
  19. Lim, D, Semyanov, A, Genazzani, A, Verkhratsky, A. Calcium signaling in neuroglia. Int Rev Cell Mol Biol. 2021;362 :1-53. doi: 10.1016/bs.ircmb.2021.01.003. PubMed PMID:34253292 .
  20. Aprile, S, Riva, B, Bhela, IP, Cordero-Sanchez, C, Avino, G, Genazzani, AA et al.. 1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry. ACS Med Chem Lett. 2021;12 (4):640-646. doi: 10.1021/acsmedchemlett.1c00034. PubMed PMID:33854704 PubMed Central PMC8040252.
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