Publications

  1. Lim, D, Dematteis, G, Tapella, L, Genazzani, AA, Calì, T, Brini, M et al.. Ca2+ handling at the mitochondria-ER contact sites in neurodegeneration. Cell Calcium. 2021;98 :102453. doi: 10.1016/j.ceca.2021.102453. PubMed PMID:34399235 .
  2. Ticci, C, Cassandrini, D, Rubegni, A, Riva, B, Vattemi, G, Matà, S et al.. Expanding the clinical and genetic spectrum of pathogenic variants in STIM1. Muscle Nerve. 2021; :. doi: 10.1002/mus.27391. PubMed PMID:34368974 .
  3. Lim, D, Semyanov, A, Genazzani, A, Verkhratsky, A. Calcium signaling in neuroglia. Int Rev Cell Mol Biol. 2021;362 :1-53. doi: 10.1016/bs.ircmb.2021.01.003. PubMed PMID:34253292 .
  4. Aprile, S, Riva, B, Bhela, IP, Cordero-Sanchez, C, Avino, G, Genazzani, AA et al.. 1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry. ACS Med Chem Lett. 2021;12 (4):640-646. doi: 10.1021/acsmedchemlett.1c00034. PubMed PMID:33854704 PubMed Central PMC8040252.
  5. Serafini, M, Cargnin, S, Massarotti, A, Tron, GC, Pirali, T, Genazzani, AA et al.. What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications. J Med Chem. 2021;64 (8):4410-4429. doi: 10.1021/acs.jmedchem.1c00181. PubMed PMID:33847110 PubMed Central PMC8154580.
  6. Nikolaeva-Koleva, M, Butron, L, González-Rodríguez, S, Devesa, I, Valente, P, Serafini, M et al.. A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability. Sci Rep. 2021;11 (1):246. doi: 10.1038/s41598-020-80725-z. PubMed PMID:33420359 PubMed Central PMC7794549.
  7. Serafini, M, Cordero-Sanchez, C, Di Paola, R, Bhela, IP, Aprile, S, Purghè, B et al.. Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors. J Med Chem. 2020;63 (23):14761-14779. doi: 10.1021/acs.jmedchem.0c01305. PubMed PMID:33253576 PubMed Central PMC7735735.
  8. Cargnin, S, Shin, JI, Genazzani, AA, Nottegar, A, Terrazzino, S. Comparative efficacy and safety of trastuzumab biosimilars to the reference drug: a systematic review and meta-analysis of randomized clinical trials. Cancer Chemother Pharmacol. 2020;86 (5):577-588. doi: 10.1007/s00280-020-04156-3. PubMed PMID:33005979 .
  9. Dionisi, M, Ruffinatti, FA, Riva, B, Lim, D, Canta, A, Meregalli, C et al.. Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification. Int J Mol Sci. 2020;21 (19):. doi: 10.3390/ijms21197164. PubMed PMID:32998392 PubMed Central PMC7584002.
  10. Dematteis, G, Vydmantaitė, G, Ruffinatti, FA, Chahin, M, Farruggio, S, Barberis, E et al.. Proteomic analysis links alterations of bioenergetics, mitochondria-ER interactions and proteostasis in hippocampal astrocytes from 3xTg-AD mice. Cell Death Dis. 2020;11 (8):645. doi: 10.1038/s41419-020-02911-1. PubMed PMID:32811809 PubMed Central PMC7434916.
  11. Ruffinatti, FA, Lomazzi, S, Nardo, L, Santoro, R, Martemiyanov, A, Dionisi, M et al.. Assessment of a Silicon-Photomultiplier-Based Platform for the Measurement of Intracellular Calcium Dynamics with Targeted Aequorin. ACS Sens. 2020;5 (8):2388-2397. doi: 10.1021/acssensors.0c00277. PubMed PMID:32701269 PubMed Central PMC8009593.
  12. Addis, A, Genazzani, A, Trotta, MP, Magrini, N, Italian Medicines Agency's Scientific Committee and COVID-19 Crisis Unit. Promoting Better Clinical Trials and Drug Information as Public Health Interventions for the COVID-19 Emergency in Italy. Ann Intern Med. 2020;173 (8):654-655. doi: 10.7326/M20-3775. PubMed PMID:32543882 PubMed Central PMC7322772.
  13. Galli, U, Colombo, G, Travelli, C, Tron, GC, Genazzani, AA, Grolla, AA et al.. Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy. Front Pharmacol. 2020;11 :656. doi: 10.3389/fphar.2020.00656. PubMed PMID:32477131 PubMed Central PMC7235340.
  14. Serafini, M, Cargnin, S, Massarotti, A, Pirali, T, Genazzani, AA. Essential Medicinal Chemistry of Essential Medicines. J Med Chem. 2020;63 (18):10170-10187. doi: 10.1021/acs.jmedchem.0c00415. PubMed PMID:32352778 PubMed Central PMC8007110.
  15. Colombo, G, Clemente, N, Zito, A, Bracci, C, Colombo, FS, Sangaletti, S et al.. Neutralization of extracellular NAMPT (nicotinamide phosphoribosyltransferase) ameliorates experimental murine colitis. J Mol Med (Berl). 2020;98 (4):595-612. doi: 10.1007/s00109-020-01892-0. PubMed PMID:32338310 .
  16. Rocchio, F, Tapella, L, Manfredi, M, Chisari, M, Ronco, F, Ruffinatti, FA et al.. Correction: Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer's disease mouse model. Cell Death Dis. 2020;11 (4):236. doi: 10.1038/s41419-020-2451-y. PubMed PMID:32300109 PubMed Central PMC7162863.
  17. Dematteis, G, Restelli, E, Chiesa, R, Aronica, E, Genazzani, AA, Lim, D et al.. Calcineurin Controls Expression of EAAT1/GLAST in Mouse and Human Cultured Astrocytes through Dynamic Regulation of Protein Synthesis and Degradation. Int J Mol Sci. 2020;21 (6):. doi: 10.3390/ijms21062213. PubMed PMID:32210081 PubMed Central PMC7139922.
  18. Torretta, S, Colombo, G, Travelli, C, Boumya, S, Lim, D, Genazzani, AA et al.. The Cytokine Nicotinamide Phosphoribosyltransferase (eNAMPT; PBEF; Visfatin) Acts as a Natural Antagonist of C-C Chemokine Receptor Type 5 (CCR5). Cells. 2020;9 (2):. doi: 10.3390/cells9020496. PubMed PMID:32098202 PubMed Central PMC7072806.
  19. Grolla, AA, Miggiano, R, Di Marino, D, Bianchi, M, Gori, A, Orsomando, G et al.. A nicotinamide phosphoribosyltransferase-GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus. J Biol Chem. 2020;295 (11):3635-3651. doi: 10.1074/jbc.RA119.010571. PubMed PMID:31988240 PubMed Central PMC7076215.
  20. Sharland, M, Gandra, S, Huttner, B, Moja, L, Pulcini, C, Zeng, M et al.. Encouraging AWaRe-ness and discouraging inappropriate antibiotic use-the new 2019 Essential Medicines List becomes a global antibiotic stewardship tool. Lancet Infect Dis. 2019;19 (12):1278-1280. doi: 10.1016/S1473-3099(19)30532-8. PubMed PMID:31782385 .
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